A comparative study of Nutritional Status among the Eastern Indian Type 2 Diabetes and Diabetic Nephropathy patients Population of West Bengal

To examine the association between nutritional status and type 2 diabetes disease phenotype in Eastern Indian patients’ population of West Bengal, the present study covered 718 participants, out of which 168 were type 2 diabetic nephropathy patients on hemodialysis (T2DNH), 246 were type 2 diabetes patients without nephropathy (T2DM) which were compared with 304 unrelated healthy controls (CON). Participants were born in Bengalee families at Kolkata and the surrounding area. Data were analyzed by the use of ANOVA and Post Hoc tests to explore the inter and intra group differences. We found that the type 2 diabetic (T2DM) and diabetic nephropathy (T2DNH) patients were relatively shorter (P for trend < 0.01) while Controls were taller (P < 0.01) and heavier (P < 0.01) than patients groups. The T2DNH patients have higher readings of systolic and diastolic blood pressure compared to T2DM patients and Controls (P < 0.01). The basal metabolic rate also differed significantly between the study groups recording relatively higher mean value among Controls (P < 0.01). As expected glucose level was significantly higher in T2DM groups (P < 0.01). Comparatively higher percentages (14.29 %) of participants were found to be underweight among the type 2 diabetic nephropathy patients group. In sum, this study directly shows a positive association between short stature with type 2 diabetes and diabetic nephropathy diseased groups of Eastern Indian population of West Bengal.