Association of Hysterectomy with Coronary Risk Factors

There is no unanimity on the association of hysterectomy with coronary risk factors. There is also no evidence on the association of hysterectomy with coronary risk factors in the Indian populations. We attempted here to investigate the association of hysterectomy with coronary risk factors involving 43 hysterectomized and 43 non-hysterectomized women. Significantly higher mean lean body mass (LBM) was observed in the hysterectomized women when compared to non-hysterectomized women (p<0.05). LBM was significantly associated with (standardized β=0.219, 95% CI 0.066-3.768,p=0.043)hysterectomy. Cut-off value of LBM was determined using receiver operator characteristic curve and found to be >38.95 kg. Univariate analysis using LBM as independent variable and coronary risk factors as dependent variables was performed. LBM cut-off value was found to be significantly associated with hypertension(p<0.05), general obesity, high waist circumference and type 2 diabetes(p<0.01). The results of the present study suggest that hysterctomized women with LBM cut-off value of >38.95kg showed association with coronary risk factors These findings need to be, however, replicated through large scale studies and/or preferably in a longitudinal study.